ALIZON Samuel

avatar
  • MIVEGEC, CNRS, Montpellier, France
  • Bioinformatics & Computational Biology, Evolutionary Applications, Evolutionary Dynamics, Evolutionary Ecology, Evolutionary Epidemiology, Evolutionary Theory, Phylogenetics / Phylogenomics
  • recommender

3 recommendations

2018-02-09
article picture
PREPRINT
Phylodynamic assessment of intervention strategies for the West African Ebola virus outbreak
Simon Dellicour, Guy Baele, Gytis Dudas, Nuno R. Faria, Oliver G. Pybus, Marc A. Suchard, Andrew Rambaut, Philippe Lemey
10.1101/163691

Recommended by Samuel Alizon based on reviews by Christian Althaus, Chris Wymant and 1 anonymous reviewer
Simulating the effect of public health interventions using dated virus sequences and geographical data

Perhaps because of its deadliness, the 2013-2016 Ebola Virus (EBOV) epidemics in West-Africa has led to unprecedented publication and sharing of full virus genome sequences. This was both rapid (90 full genomes were shared within weeks [1]) and important (more than 1500 full genomes have been released overall [2]). Furthermore, the availability of the metadata (especially GPS location) has led to depth analyses of the geographical spread of the epidemics [3].
In their work, Dellicour et al. [...

More
2017-06-12
article picture
PREPRINT
Evolution and manipulation of vector host choice
Sylvain Gandon
10.1101/110577

Recommended by Samuel Alizon based on reviews by Samuel Alizon and Nicole Mideo
Modelling the evolution of how vector-borne parasites manipulate the vector's host choice

Many parasites can manipulate their hosts, thus increasing their transmission to new hosts [1]. This is particularly the case for vector-borne parasites, which can alter the feeding behaviour of their hosts. However, predicting the optimal strategy is not straightforward because three actors are involved and the interests of the parasite may conflict with that of the vector. There are few models that consider the evolution of host manipulation by parasites [but see 2-4], but there are virtually ...

More
2016-12-17
article picture
Evolution of HIV virulence in response to widespread scale up of antiretroviral therapy: a modeling study
Herbeck JT, Mittler JE, Gottlieb GS, Goodreau SM, Murphy JT, Cori A, Pickles M, Fraser C
10.1093/ve/vew028

Recommended by Samuel Alizon and Roger Kouyos
Predicting HIV virulence evolution in response to widespread treatment

It is a classical result in the virulence evolution literature that treatments decreasing parasite replication within the host should select for higher replication rates, thus driving increased levels of virulence if the two are correlated. There is some evidence for this in vitro but very little in the field. HIV infections in humans offer a unique opportunity to go beyond the simple predictions that treatments should favour more virulent strains because many details of this host-parasite syste...

More

1 review

2017-06-12
article picture
PREPRINT
Evolution and manipulation of vector host choice
Sylvain Gandon
10.1101/110577

Recommended by Samuel Alizon based on reviews by Samuel Alizon and Nicole Mideo
Modelling the evolution of how vector-borne parasites manipulate the vector's host choice

Many parasites can manipulate their hosts, thus increasing their transmission to new hosts [1]. This is particularly the case for vector-borne parasites, which can alter the feeding behaviour of their hosts. However, predicting the optimal strategy is not straightforward because three actors are involved and the interests of the parasite may conflict with that of the vector. There are few models that consider the evolution of host manipulation by parasites [but see 2-4], but there are virtually ...

More