ENGELSTAEDTER Jan

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  • Evolution, Sex & Parasites lab, The University of Queensland, Brisbane, Australia
  • Bioinformatics & Computational Biology, Evolutionary Dynamics, Evolutionary Epidemiology, Evolutionary Theory, Experimental Evolution, Population Genetics / Genomics, Reproduction and Sex, Species interactions
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2020-05-18
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The insertion of a mitochondrial selfish element into the nuclear genome and its consequences
Julien Y. Dutheil, Karin Münch, Klaas Schotanus, Eva H. Stukenbrock and Regine Kahmann
10.1101/787044

Recommended by Sylvain Charlat based on reviews by Jan Engelstaedter and Yannick Wurm
Some evolutionary insights into an accidental homing endonuclease passage from mitochondria to the nucleus

Not all genetic elements composing genomes are there for the benefit of their carrier. Many have no consequences on fitness, or too mild ones to be eliminated by selection, and thus stem from neutral processes. Many others are indeed the product of selection, but one acting at a different level, increasing the fitness of some elements of the genome only, at the expense of the “organism” as a whole. These can be called selfish genetic elements, and come into a wide variety of flavours [1], il...

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