MANK Judith

  • Dept Genet Evol Environ, Univ. College London, London, United Kingdom
  • Evolutionary Ecology, Expression Studies, Genome Evolution, Genotype-Phenotype, Population Genetics / Genomics, Reproduction and Sex, Sexual Selection
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Genomic imprinting mediates dosage compensation in a young plant XY system
Aline Muyle, Niklaus Zemp, Cecile Fruchard, Radim Cegan, Jan Vrana, Clothilde Deschamps, Raquel Tavares, Franck Picard, Roman Hobza, Alex Widmer, Gabriel Marais

Recommended by Tatiana Giraud and Judith Mank based on reviews by 3 anonymous reviewers
Dosage compensation by upregulation of maternal X alleles in both males and females in young plant sex chromosomes

Sex chromosomes evolve as recombination is suppressed between the X and Y chromosomes. The loss of recombination on the sex-limited chromosome (the Y in mammals) leads to degeneration of both gene expression and gene content for many genes [1]. Loss of gene expression or content from the Y chromosome leads to differences in gene dose between males and females for X-linked genes. Because expression levels are often correlated with gene dose [2], these hemizygous genes have a lower expression leve...


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