Adaptation, Evolutionary Epidemiology, Experimental Evolution, Genotype-Phenotype, Molecular Evolution, Phylogenetics / Phylogenomics, Population Genetics / Genomics, Quantitative Genetics, Species interactions
I am working on the durability of plant resistance to pathogens (especially viruses) using multiple approaches (genetics, experimental evolution, epidemiology, population genetics and modelling).
Genetic drift, purifying selection and vector genotype shape dengue virus intra-host genetic diversity in mosquitoes Lequime S, Fontaine A, Gouilh MA, Moltini-Conclois I and Lambrechts L http://dx.doi.org/10.1371/journal.pgen.1006111
Many viruses are transmitted by biological vectors, i.e. organisms that transfer the virus from one host to another. Dengue virus (DENV) is one of them. Dengue is a mosquito-borne viral disease that has rapidly spread around the world since the 1940s. One recent estimate indicates 390 million dengue infections per year . As many arthropod-borne vertebrate viruses, DENV has to cross several anatomical barriers in the vector, to multiply in its body and to invade its salivary glands before gett...