SPENCER Hamish G.

  • NA, Univ. of Otago, Dunedin, New Zealand
  • Evolutionary Theory, Non Genetic Inheritance, Phylogeography & Biogeography, Population Genetics / Genomics, Systematics / Taxonomy
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I am professor in the Department of Zoology, where I carry research out research on a wide variety of topics, from population genetic theory (models of selection and the maintenance of genetic variation; models of selection on non-standard inheritance systems; models of phenotypic plasticity), to biogeography (long-distance dispersal in marine invertebrates) and phylogeny (of cormorants and molluscs), to the history of eugenics. My obtained my PhD from Harvard University, studying under Richard Lewontin; my undergraduate degree was in mathematics from the University of Auckland, from which I also graduated with an MSc in zoology, studying with David Lambert and Brian McArdle.

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2017-11-20
PREPRINT
Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection
Diala Abu Awad and Denis Roze
https://doi.org/10.1101/180000

Recommended by Aneil F. Agrawal based on reviews by Frédéric Guillaume and 1 anonymous reviewer
Understanding genetic variance, load, and inbreeding depression with selfing

A classic problem in evolutionary biology is to understand the genetic variance in fitness. The simplest hypothesis is that variation exists, even in well-adapted populations, as a result of the balance between mutational input and selective elimination. This variation causes a reduction in mean fitness, known as the mutation load. Though mutation load is difficult to quantify empirically, indirect evidence of segregating genetic variation in fitness is often readily obtained by comparing the f...

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