GUILLAUME Frédéric

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  • , University of Zurich, Zurich, Switzerland
  • Adaptation, Evolutionary Dynamics, Evolutionary Theory, Genotype-Phenotype, Phenotypic Plasticity, Population Genetics / Genomics, Quantitative Genetics
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1 recommendation

2019-12-09
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Trait-specific trade-offs prevent niche expansion in two parasites
Eva JP Lievens, Yannis Michalakis, Thomas Lenormand
10.1101/621581

Recommended by Frédéric Guillaume based on reviews by Seth Barribeau, Anne Duplouy and Cindy Gidoin
Trade-offs in fitness components and ecological source-sink dynamics affect host specialisation in two parasites of Artemia shrimps

Ecological specialisation, especially among parasites infecting a set of host species, is ubiquitous in nature. Host specialisation can be understood as resulting from trade-offs in parasite infectivity, virulence and growth. However, it is not well understood how variation in these trade-offs shapes the overall fitness trade-off a parasite faces when adapting to multiple hosts. For instance, it is not clear whether a strong trade-off in one fitness component may sufficiently constrain the evolu...

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1 review

2017-11-20
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Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection
Diala Abu Awad and Denis Roze
10.1101/180000

Recommended by Aneil F. Agrawal based on reviews by Frédéric Guillaume and 1 anonymous reviewer
Understanding genetic variance, load, and inbreeding depression with selfing

A classic problem in evolutionary biology is to understand the genetic variance in fitness. The simplest hypothesis is that variation exists, even in well-adapted populations, as a result of the balance between mutational input and selective elimination. This variation causes a reduction in mean fitness, known as the mutation load. Though mutation load is difficult to quantify empirically, indirect evidence of segregating genetic variation in fitness is often readily obtained by comparing the f...

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