• Laboratory of Molecular Evolution, Skolkovo Institute of Science and Technology, Moscow, Russia
  • Adaptation, Bioinformatics & Computational Biology, Evolutionary Dynamics, Evolutionary Theory, Genome Evolution, Human Evolution, Molecular Evolution, Population Genetics / Genomics
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Associate Professor, Skolkovo Institute of Science and Technology, Moscow, Russia, since 2018 (Assistant Professor since 2016) Head of Sector of Molecular Evolution, Kharkevitch Institute for Information Transmission Problems of the Russian Academy of Sciences, Moscow, Russia, since 2007 Leading researcher, Lomonosov Moscow State University, Moscow, Russia, since 2011 D.Sc. in Biology, 2018 PhD in Ecology and Evolution, Princeton University, 2007 Diploma (B.S.) in Biology, Moscow State University, 2001

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Is adaptation limited by mutation? A timescale-dependent effect of genetic diversity on the adaptive substitution rate in animals
Marjolaine Rousselle, Paul Simion, Marie-Ka Tilak, Emeric Figuet, Benoit Nabholz, Nicolas Galtier

Recommended by Georgii Bazykin based on reviews by David Enard, Konstantin Popadin and 1 anonymous reviewer
To tinker, evolution needs a supply of spare parts

Is evolution adaptive? Not if there is no variation for natural selection to work with. Theory predicts that how fast a population can adapt to a new environment can be limited by the supply of new mutations coming into it. This supply, in turn, depends on two things: how often mutations occur and in how many individuals. If there are few mutations, or few individuals in whom they can originate, individuals will be mostly identical in their DNA, and natural selection will be impotent.
This th...


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