|2020-07-27 ||Evolution of the DAN gene family in vertebrates|
Juan C. Opazo, Federico G. Hoffmann, Kattina Zavala, Scott V. Edwards
Recommended by Kateryna Makova based on reviews by 2 anonymous reviewers
An evolutionary view of a biomedically important gene family
This manuscript  investigates the evolutionary history of the DAN gene family—a group of genes important for embryonic development of limbs, kidneys, and left-right axis speciation. This gene family has also been implicated in a number of diseases, including cancer and nephropathies. DAN genes have been associated with the inhibition of the bone morphogenetic protein (BMP) signaling pathway. Despite this detailed biochemical and functional knowledge and clear importance for development and ...
|2019-06-11 ||A bird’s white-eye view on neosex chromosome evolution|
Thibault Leroy, Yoann Anselmetti, Marie-Ka Tilak, Sèverine Bérard, Laura Csukonyi, Maëva Gabrielli, Céline Scornavacca, Borja Milá, Christophe Thébaud, Benoit Nabholz
Recommended by Kateryna Makova based on reviews by Gabriel Marais, Melissa Wilson and 1 anonymous reviewer
Young sex chromosomes discovered in white-eye birds
Recent advances in next-generation sequencing are allowing us to uncover the evolution of sex chromosomes in non-model organisms. This study  represents an example of this application to birds of two Sylvioidea species from the genus Zosterops (commonly known as white-eyes). The study is exemplary in the amount and types of data generated and in the thoroughness of the analysis applied. Both male and female genomes were sequenced to allow the authors to identify sex-chromosome specific scaf...