Title

Negative frequency-dependent selection is frequently confoundinguse asterix (*) to get italics

Authors

Dustin BrissonPlease use the format "First name initials family name" as in "Marie S. Curie, Niels H. D. Bohr, Albert Einstein, John R. R. Tolkien, Donna T. Strickland"

Year

2017

Picture

Abstract

The existence of persistent genetic variation within natural populations presents an evolutionary problem as natural selection and genetic drift tend to erode genetic diversity. Models of balancing selection were developed to account for the high and sometimes extreme levels of polymorphism found in many natural populations. Negative frequency-dependent selection may be the most powerful selective force maintaining balanced natural polymorphisms but it is also commonly misinterpreted. The aim of this review is to clarify the processes underlying the negative frequency-dependent selection model, describe classes of natural polymorphisms that can and cannot result from these processes, and discuss observational and experimental data that can aid in accurately identifying the processes that generated or are maintain diversity in nature. Finally, I consider the importance of accurately describing the processes affecting genetic diversity within populations as it relates to research progress.

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Keywords

Balancing selection, Negative frequency dependent selection

Methods that require specific expertise (optional)

NonePlease indicate the methods that may require specialised expertise during the peer review process (use a comma to separate various required expertises).

Thematic fields

Evolutionary Applications, Evolutionary Theory, Population Genetics / Genomics

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Submission date

2017-03-03 18:46:42

Recommender

Ignacio Bravo

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Juan Arroyo
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Marianne Elias
Inês Fragata
Matteo Fumagalli
Tatiana Giraud
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Ruth Hufbauer
Sara Magalhaes
Caroline Nieberding
Michael David Pirie
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