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Masculinization of the X-chromosome in aphid soma and gonadsuse asterix (*) to get italics
Julie Jaquiery, Jean-Christophe Simon, Stephanie Robin, Gautier Richard, Jean Peccoud, Helene Boulain, Fabrice Legeai, Sylvie Tanguy, Nathalie Prunier-Leterme, Gael LetrionnairePlease use the format "First name initials family name" as in "Marie S. Curie, Niels H. D. Bohr, Albert Einstein, John R. R. Tolkien, Donna T. Strickland"
2022
<p>Males and females share essentially the same genome but differ in their optimal values for many phenotypic traits, which can result in intra-locus conflict between the sexes. Aphids display XX/X0 sex chromosomes and combine unusual X chromosome inheritance with cyclical parthenogenesis. Theoretical and empirical works support the hypothesis that the large excess of male-biased genes observed on the aphid X chromosome compared to autosomes evolved in response to sexual conflicts, by restricting the products of sexually antagonistic alleles to the sex they benefits. However, whether such masculinization of the X affects all tissues (as expected if it evolved in response to sexual conflicts) or is limited to specific tissues remains an open question. Here, we measured gene expression in three different somatic and gonadic tissues of males, sexual females and parthenogenetic females of the pea aphid. We observed a masculinization of the X in each of the studied tissues, with male-biased genes being 2.5 to 3.5 more frequent on the X than expected. We also tested the hypothesis that gene duplication can facilitate the attenuation of conflicts by allowing gene copies to neo- or sub-functionalize and reach sex-specific optima. As predicted, X-linked copies of duplicated genes having their other copies on autosomes were more frequently male-biased (40.5% of the genes) than duplicated autosomal genes (6.6%) or X-linked single-copy genes (32.5%). These results highlight a peculiar pattern of expression of X-linked genes in aphids at the tissue level and provide further support for sex-biased expression as a mechanism to attenuate intra-locus sexual conflicts.</p>
https://doi.org/10.5281/zenodo.6242803You should fill this box only if you chose 'All or part of the results presented in this preprint are based on data'. URL must start with http:// or https://
https://doi.org/10.5281/zenodo.6242803You should fill this box only if you chose 'Scripts were used to obtain or analyze the results'. URL must start with http:// or https://
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Sex-biased gene expression, sexual conflict, sexual antagonism, dimorphism, sex chromosome, duplication
NonePlease indicate the methods that may require specialised expertise during the peer review process (use a comma to separate various required expertises).
Genetic conflicts, Genome Evolution, Reproduction and Sex
No need for them to be recommenders of PCIEvolBiol. Please do not suggest reviewers for whom there might be a conflict of interest. Reviewers are not allowed to review preprints written by close colleagues (with whom they have published in the last four years, with whom they have received joint funding in the last four years, or with whom they are currently writing a manuscript, or submitting a grant proposal), or by family members, friends, or anyone for whom bias might affect the nature of the review - see the code of conduct
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2021-08-16 08:56:08
Charles Baer